By P. Dawson PhD, MRCP, FRCR (auth.), P. Dawson, W. Clauss (eds.)
For all that new non-X-ray applied sciences akin to MR and ultrasound and its a variety of manifestations have made a tremendous effect lately at the perform of scientific imaging, using X-rays and X-ray contrast-enhancing brokers has retained a big place on the middle of the method. certainly, with its widespread specifications for top overall dose regimes, CT has elevated using distinction brokers. Even helical/spiral CT which, it used to be first and foremost argued, should still decrease distinction in addition to radiation a lot, may very well require simply as a lot or extra of either as a result of capability it deals for multi-phase scanning.
Iodinated intravascular X-ray distinction brokers, specially the extra lately constructed non-ionic brokers, proceed consequently to play a pivotal position in scientific imaging.
those succinct and authoritative articles, initially showing within the magazine Advances in X-ray Contrast, diversity sufficiently generally for his or her compilation during this quantity to be thought of a mini-textbook at the water-soluble iodinated X-ray distinction brokers and their functions. every one is written through an said and skilled specialist within the box. They usefully disguise the developmental heritage of the brokers; outlined chance elements, methods to prophylaxis and, eventually, of the remedy of difficult reactions; the attention-grabbing topic of meant not on time reactions to distinction brokers; the real organ-specific toxicities, cardiac toxicity, neurotoxicity and nephrotoxicity and high-dose toxicity as encountered in advanced tactics; the occasionally designated conditions and coffee severe stipulations to which distinction brokers could be uncovered in Interventional Radiology; the distinctive, in numerous methods, case of paediatric radiology; the arguable topic of thromboembolic phenomena in scientific angiography; and the perfect position of distinction brokers. As regards the practicalities of distinction management regimes and imaging protocols it truly is purely within the zone of CT that there's debate and controversy, and articles are incorporated which hide CT of the liver, spleen and pancreas, and protocols for the recent spiral/helical know-how or even for the less largely on hand electron-beam CT know-how visualization. Pulmonary embolus prognosis and protocols for distinction management with this expertise also are discussed.
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Additional info for Advances in X-Ray Contrast: Collected Papers
1988; 23: S351-S358. Dawson P. Chemotoxicity of contrast agents and clinical adverse effects. Invest Radiol985; 20: 584-591. Dahlborn M, Crone strand R, Klintmal G, Sundelins S. Blood inflow and coagulation in vascular catheters: comparison of the effects of polysaccharide solutions, saline and contrast medium. Acta Radiol [DiagnJ (Stockh). 1980; 21: 715-720. Hwang MH, Piao ZE, Murdock DK, Messmore HL, Giardina JJ, Scanlon PJ. Risk of thromboembolism during diagnostic and interventional cardiac procedures with non-ionic contrast media.
Elliott C, Reger M. Acute renal failure following low osmolality radiocontrastdye. C1in Cardiol. 1988; II: 420-422. Dawson P. On the nephrotoxic potential of the iodinated intravascular contrast agents. Adv X-ray Contrast. 1993; I: 29. This paper was first published in Advances in X-Ray Contrast. 1993;1:54-57. 33 UPDATE Since the above text was written there has been a small number of new papers on the subject. The most important is a paper on acute and late adverse reactions to low osmolar contrast media by Mikkonen et al.
Arch Intern Med 1978; 138: 1430-1432. Perdue GD, Smith RB. Atheromatous microemboli. Ann Surg. 1969; 169:954-959. Hessel SJ, Adams DE, Abrams ML. Complications of angiography. Radiology. 1981;138: 273-281. Katzen BT. Interventional and diagnostic therapeutic procedures. New York: Springer-Verlag; 1980: 2-3. Robertson HJF. Blood clot formation in angiographic syringes containing nonionic contrast media. Radiology. (j22. Bernstein EF, Gans H. Anticoagulant activities of angiographic contrast media.