Download An Atlas of Parkinson's Disease and Related Disorders by Perkin G David PDF

By Perkin G David

ISBN-10: 1850709432

ISBN-13: 9781850709435

Any dialogue of the medical features of Parkinson's ailment needs to consider the inaccuracies of medical analysis. In a successive sequence of a hundred sufferers with a medical prognosis of Parkinson's illness, purely seventy six fulfilled the factors for prognosis at autopsy exam. makes an attempt to tighten the diagnostic standards bring about elevated specificity yet with decreased sensitivity.In An Atlas of Parkinson's illness and similar issues Dr. David Perkin has compiled a chain of images highlighting numerous features of Parkinson's sickness and similar motor problems. The booklet offers an invaluable pattern of medical, investigative (CT, MRI, and puppy) and pathological pictures with succinct descriptive textual content of the problems featured. nearly one-third of the fabric during this booklet is pathological, incorporating either macroscopic and microscopic sections. a different zone of the cloth is represented via imaging, largely magnetic resonance imaging (MRI) and positron emission tomography (PET) scanning. the world of stream issues has been rather fruitful for puppy scanning, which supplies, with the advance of particular ligands for a number of the receptor websites, to additional extend knowing of the pathophysiological mechanisms of the circulate issues. Reflecting the top criteria scientific images and imaging in addition to the celebrated author's professional wisdom of the topic, Dr. Perkin's An Atlas of Parkinson's affliction and comparable problems is the definitive and crucial scientific reference in its box.

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Extra info for An Atlas of Parkinson's Disease and Related Disorders (Encyclopedia of Visual Medicine Series)

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Atrophy of the central white matter in the cerebellar folia is also seen. Evidence of Purkinje cell degeneration (right) with formation of axon torpedoes (white arrow) is seen in the molecular layer (H & Es) ©2004 CRC Press LLC Figure 40 Histological sections showing examples of oligodendroglial cytoplasmic inclusions in multiple system atrophy (H & Es) ©2004 CRC Press LLC Figure 41 Sagittal T1-weighted MRI showing pontine (black arrow) and cerebellar (white arrow) atrophy in a patient with olivopontocerebellar atrophy ©2004 CRC Press LLC Figure 42 T2-weighted MRI (upper) shows hyperintensity of the middle cerebellar peduncles and the cerebellum.

11C-raclopride is a selective reversible antagonist of D2 receptors) Figure 33 Coronal section of brain from a patient with striatonigral degeneration showing symmetrical atrophy and discoloration of the putamen ©2004 CRC Press LLC Figure 34 Histology of striatonigral degeneration shows atrophy of the putamen with rarefaction and gliosis (H & E) Figure 35 Transverse section of midbrain in striatonigral degeneration shows pallor of the substantia nigra ©2004 CRC Press LLC Figure 36 Axial (upper) and coronal (lower) T2-weighted MRIs showing putaminal hypointensity (arrowed) in a patient with striatonigral degeneration ©2004 CRC Press LLC Figure 37 Coronal sections showing normal (upper) compared with atrophied (lower) basis pontis secondary to olivopontocerebellar atrophy in multiple system atrophy Figure 38 Histological sections of basis pontis (arrowed) show the normal complement of pontine neurons in a control subject (left) compared with neuronal depletion (right) in multiple system atrophy (H & Es) ©2004 CRC Press LLC Figure 39 Multiple system atrophy with olivopontocerebellar atrophy.

Evidence of Purkinje cell degeneration (right) with formation of axon torpedoes (white arrow) is seen in the molecular layer (H & Es) ©2004 CRC Press LLC Figure 40 Histological sections showing examples of oligodendroglial cytoplasmic inclusions in multiple system atrophy (H & Es) ©2004 CRC Press LLC Figure 41 Sagittal T1-weighted MRI showing pontine (black arrow) and cerebellar (white arrow) atrophy in a patient with olivopontocerebellar atrophy ©2004 CRC Press LLC Figure 42 T2-weighted MRI (upper) shows hyperintensity of the middle cerebellar peduncles and the cerebellum.

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