By Dennis P. O'Malley (auth.)
The spleen is an organ which has varied services together with immunologic and hematologic. The Atlas of Spleen Pathology describes and selectively illustrates the conventional and pathologic stipulations that afflict the spleen. This amazing selection of prime quality electronic pictures will materially reduction in carrying on with efforts to acknowledge, comprehend, and appropriately interpret the gross and light-weight microscopic findings in spleens.
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Additional resources for Atlas of Spleen Pathology
Image courtesy of D. ) Fig. 135 Diffuse large B-cell lymphoma. Gross image of spleen (upper) and diffuse large B-cell lymphoma with massive involvement of splenic hilar lymph node. Note the uniform pink, fleshy appearance of lymphoma compared to the deep red of normal splenic parenchyma. (Image courtesy of A. ) 3 Lymphoid Neoplasms Fig. 136 Diffuse large B-cell lymphoma. Gross image of diffuse large B-cell lymphoma of spleen. Areas of necrosis are present that impart a chalky, pale appearance to the otherwise fleshy pink of the lymphoma.
112 T-cell large granular lymphocytic leukemia. Another example of high magnification in T-cell large granular lymphocytic leukemia. 13 T-cell Large Granular Lymphocytic Leukemia Fig. 113 T-cell large granular lymphocytic leukemia. Another high magnification image of T-cell large granular lymphocytic leukemia. In this case, a granulocyte is present (middle, lower), which suggests the size (mostly small) of the abnormal lymphoid cells 45 Fig. 116 NK-cell large granular lymphocytic leukemia. Another low magnification of a chronic leukemia of NK cells in the spleen.
These lymphoma cells are within cords and sinuses, with many interspersed small lymphocytes (likely T cells) and macrophages Fig. 144 Diffuse large B-cell lymphoma. Diffuse large B-cell lymphoma (left) adjacent to an area of coagulative necrosis (right). The lymphoma cells have a diffuse pattern. The areas of necrosis show cell ghosts. Likely there was compromise of the vascular supply leading to the area of necrosis Fig. 143 Diffuse large B-cell lymphoma. Diffuse large B-cell lymphoma adjacent to splenic capsule.